Dengue Outbreaks 2023

Authored by
Last reviewed
February 7, 2023
Content Overview
Dengue outbreaks occur worldwide in 2023. There are two approved dengue vaccines available in certain countries.

Dengue Outbreaks 2023

According to the U.S. Centers for Disease Control and Prevention (CDC), dengue is a vectorborne infectious disease caused by dengue viruses, predominantly transmitted by mosquitos, and is endemic in about 125 countries. Dengue is present in Asia, the Pacific, the Caribbean, the Americas, and Africa, says the European Centre for Disease Prevention and Control (ECDC).

The Pan American Health Organization (PAHO) Epidemiological Update (Feb. 2023), FloridaPuerto Rico, and the U.S. Virgin Islands health departments highlight new dengue cases. Previously, the CDC had issued Watch-Level 1, Practice Usual Precautions alerts regarding dengue outbreaks in the Americas, Africa, Costa Rica, the Middle East, and the Pacific IslandsCanada and the United Kingdom also issued dengue travel advisories in 2023.

Dengue in the U.S.

Provisional data published by the U.S. CDC as of February 3, 2023, indicates about 16 travel-related and (0) locally-acquired dengue cases were reported by U.S. states in 2023. In addition, the CDC says dengue is endemic in the U.S. territories of Puerto Rico, American Samoa, the U.S. Virgin Islands, the Federated States of Micronesia, the Republic of Marshall Islands, and the Republic of Palau, where eight travel and 820 local cases were confirmed in 2022.

Dengue in Florida

As of February 2023, the Florida Health Department reported 869 travel-associated and 68 locally-acquired dengue cases in 2022. In 2023, fourteen travel-associated dengue fever cases were reported in week #4. During the summer of 2022, the Florida Department of Health in Miami-Dade County was under a mosquito-borne illness advisory. Most dengue (DENV-3) cases were confirmed in Miami-Dade County. And in Broward County, a mosquito-borne illness alert was issued. Until 2009, there were no reports of dengue acquired in Florida since 1934. However, in 2009 -2010, an outbreak of dengue was identified in 22 people in Key West.

Dengue in Puerto Rico

As of January 2023, Puerto Rico's Department of Health Arboviral Disease reported 929 confirmed dengue cases and three related fatalities in 2022. In 2023, Report #4 shows nine dengue cases this year. From 2010 to 2020, approximately 95% of locally acquired dengue cases in the U.S. (n = 31,289) occurred near San Juan, Puerto Rico (n = 29,779).

Dengue in Mexico 2023

Mexico is reported in 28 of 32 states and accounts for about 1.7–21.1% of dengue-related deaths in the Americas. Throughout Mexico, the PAHO reported 36,926 cases, and 53 dengue deaths (Sonora confirmed 14 deaths, Oaxaca 13 deaths) were confirmed in 2022. Dengue transmission has been documented in Yucatan, Mexico since 1979. The recent increase in dengue cases has been partly attributed to the genetic diversification of DENV serotypes and the emergence of new genotypes across Latin America (Hernández-García et al., 2020).

Dengue in the Americas

In the Region of the Americas, 46 countries and territories reported dengue cases to the Pan American Health Organization (PAHO) in 2022. Of note, the countries with the most severe dengue cases included the U.S. (1.46%), Honduras (.76%), Colombia (.99%), Paraguay (.21%), Dominican Republic (.89%), Grenada (2.93%), Puerto Rico, (3.51%), British Virgin Islands, (9.09%).

Dengue Endemic Countries

The WHO says 400 million dengue infections occur yearly, about 80% mild and/or asymptomatic. The European CDC published Situation Update #660 on December 1, 2022. The ECDC reported as of August 2022, over 2,5 million cases and 2,065 fatalities have been confirmed, led by Brazil (1,910,657), Vietnam (145,536), Philippines (82,597), Indonesia (68,903), Peru (57,469).

As of December 2022, a total of 61,972 laboratory-confirmed dengue cases and 274 related fatalities (CFR 0.44%) have been reported by the Ministry of Health & Family Welfare of Bangladesh in 2022. In addition, on November 16, 2022, GAVI reported Dengue fever is endemic in Pakistan. And in 2021, a total of 1,64,103 dengue cases were reported in India.

Dengue Vaccines

Authorized dengue vaccines (Qdenga and Dengvaxia) and vaccine candidates' information can be found at

Dengue Fever

Dengue fever is caused by four closely related viruses (DENV-1–4), and a person can be infected with each serotype for a total of four infections during their lifetime. There is no specific treatment for dengue/severe dengue, says the U.S. CDC.